CYSTIC FIBROSIS Early detection of cystic fibrosis lung disease: multiple-breath washout versus raised volume tests
نویسندگان
چکیده
Sooky Lum, Per Gustafsson, Henrik Ljungberg, Georg Hülskamp, Andrew Bush, Siobhán B Carr, Rosemary Castle, Ah-fong Hoo, John Price, Sarath Ranganathan, John Stroobant, Angie Wade, Colin Wallis, Hilary Wyatt, Janet Stocks on behalf of the London Cystic Fibrosis Collaboration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
منابع مشابه
Early detection of cystic fibrosis lung disease: multiple-breath washout versus raised volume tests.
BACKGROUND Lung clearance index (LCI), a measure of ventilation inhomogeneity derived from the multiple-breath inert gas washout (MBW) technique, has been shown to detect abnormal lung function more readily than spirometry in preschool children with cystic fibrosis, but whether this holds true during infancy is unknown. OBJECTIVES To compare the extent to which parameters derived from the MBW...
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Many children with cystic fibrosis (CF), receiving modern, aggressive CF care, have normal spirometry results. This study aimed to see if homogeneity of ventilation distribution is impaired early in the course of CF lung disease, and if ventilation inhomogeneity is a more frequent finding than abnormal spirometry in children benefiting from modern CF care. The study compared spirometry findings...
متن کاملEarly detection of cystic fibrosis lung disease: multiple breath washout vs. raised volume tests
Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL, Institute of Child Health, London. Department of Pediatric Clinical Physiology, Queen Silvia Children’s Hospital, Göteborg, Sweden. Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London. Department of Child Health, Royal London Hospital, London. Department of Paediatric Respiratory Medicine, Great...
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Background Pulmonary involvement is the main cause of mortality in cystic fibrosis (CF). Airway clearance techniques are non-pharmacological complement options for CF patients. The aim of this study was to evaluate the short-term outcome of airway cleaning treatment in patients with cystic fibrosis in a children's hospital. Materials and Methods This clinical trial study conducted on 40 CF pati...
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In the quest to investigate small airway function in a range of lung diseases, multiple-breath washout tests have been applied for their potential to represent the most peripheral air spaces [1, 2]. The aim of reducing the burden on the patient has recently also revived interest in the single-breath washout. A single-breath washout test has now been proposed which involves an inhalation of 5% S...
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